Ilexhainanoside D

Research use only, not for human use.

Ilexhainanoside D is a natural product from Periploca sepiumBge.

Ilexhainanoside D is a natural product from Periploca sepiumBge.

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The combination of Ilexhainanoside D and Ilexsaponin A (60, 120 or 240?mg/kg; for 8 weeks) treatment significantly reduces the severity of non-alcoholic fatty liver disease (NAFLD) induced by high-fat diet in a dose-dependent manner. The combination of Ilexhainanoside D and Ilexsaponin A treatment decreases the ratio of Firmicutes/Bacteroidetes, reduces the relative abundance of Desulfovibrio and increases the relative abundance of Akkermansia. The intestinal barrier is improved as evidenced by the upregulation of the expression of zonula occludens-1 (ZO-1) and occludin in the ileum. The combination of Ilexhainanoside D and Ilexsaponin A treatment reduces the entry of LPS into the circulation and decreases the hepatic gene expression levels of proinflammatory cytokines.

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Others

Other Targets

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1137648-52-2

664.83

C36H56O11

>98% (HPLC)

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(-20℃)

With Ice Pack

≥ 2 years